Publications

 1.     Turk L. S., Kuang X., Pozzo V. D., Khush Patel K., Chen M., Huynh K., Currie M. J., Mitchell D., Dobson, R., D’Arcangelo G., Dai W.*, Davide Comoletti D.* (2021), The structure - function relationship of a signaling competent, dimeric Reelin fragment, Structure. S0969-2126 (21)00170-2. Doi: 10.1016/j.str.2021.05.012. 2.     Jiang J., Cheong K. Y., Falkowski P. G., Dai, W. (2021), Integrating On-grid Immunogold labeling and Cryo-Electron Tomography to Reveal Photosystem II Structure and Spatial Distribution in Thylakoid Membranes, J. Struct. Biol. 107746. Doi: 10.1016/j.jsb.2021.107746 3.     Kuang, X., Nunn, K., Jiang, J., Castellano, P., Hardikar, U., Horgan, A., Kong, J., Tan, Z., Dai, W. (2021), Structural insight into transmissive mutant huntingtin species by correlative light and electron microscopy and cryo-electron tomography, Biochem Biophys Res Commun. 560: 99-104. 4.     Jiménez-Ortigosa C., Jiang J., Chen M., Kuang, X., Healey K. R., Castellano P., Boparai N., Ludtke S. J., Perlin D. S., and Dai W. (2021), Preliminary structural elucidation of β-(1,3)-glucan synthase from candida glabrata using cryo-electron tomography. JOF 7 (2), 120. 5.     Nunn, K., Castellano, P., Jiang, J., Tan, Z., Dai, W. (2021), Visualizing Transmissive Mutant Huntingtin by Correlative Light and Electron Microscopy and Cryo-electron Tomography. Microsc. Microanal., 27 (S1): 6.     Nunn, K., Kuang, X., Castellano, P., Jiang, J., Horgan, A., Kong, J., Tan, Z., Dai, W. (2021), Extracellular Vesicles Modulate Formation of Transmissive Mutant Huntingtin Assemblies. Microsc. Microanal., 27 (S1): 7.     Muscarella A. M., Dai W., Mitchell P. G, Zhang W., Wang H., Jia L., Stossi F., Mancini M., Chiu W., and Zhang X. H.-F, (2020), Unique cellular protrusions mediate breast cancer cell migration by tethering to osteogenic cells. npj Breast Cancer 6: 42. 8.     Levitan O., Chen M., Kuang X., Cheong K. Y., Jiang J., Banal M., Nambiar N., Ludtke S. J., Falkowski P. G., and Dai W. (2019), Structural and functional analyses of photosystem II reaction centers in thylakoid membranes of a marine diatom. PNAS, 116 (35): 17316 - 17322. 9.     Hernández N. E., Hansen W. A, Zhu D., Shea M.E., Manichev V., Putnins M., Chen M., Anthony G. Dodge A. G., Yang L., Banal M., Gustafsson T., Leonard C. Feldman L. C., Lee S., Wackett L. P., Dai W. and Khare S., (2019), Stimulus-responsive self-assembly of protein based fractals by computational design, Nat. Chem., 11 (7): 605-614. 10.   Chen J. Y., Parekh M., Seliman H., Bakshinskaya D., Dai W., Kwan K., Chen K. Y., Liu A. Y. C., (2018), Heat shock promotes inclusion body formation of mutant huntingtin (mHtt) and alleviates mHtt-induced transcription factor dysfunction, J. Biol. Chem.,293: 15581-15593.  11.  Dai W., Chen M., Myers C., Ludtke S. J., Pettitt B. M., King J. A., Schmid M. F., Chiu W., (2018), Visualizing individual RuBisCO and its assembly into carboxysomes in marine cyanobacteria by cryo-electron tomography. J. Mol. Biol., 430 (21): 4156-4167. 12.  Chen, M., Dai, W., Sun, S. Y., Jonasch, D., He, C. Y., Schmid, M. F., Chiu, W., and Ludtke, S. J., (2017), Convolutional neural networks for automated annotation of cellular cryo-electron tomograms. Nature Methods. 14: 983-985 13.  Chen, M., Dai, W., Sun, S. Y., Schmid, M. F., Chiu, W., and Ludtke, S. J., (2017), Going deeper in cryo electron tomography with neural networks. Microsc. Microanal., 23 (S1), 814-815 14.  Luengo, I., Darrow, M.C., Spink, M.C., Sun, Y., Dai, W., He, C.Y., Chiu, W., Pridmore, T., Ashton, A.W., Duke, E.M.H., Basham, M., Andrew P. French, A.P, (2017). SuRVoS: super-region volume segmentation workbench. J. Struct. Biol. 198 (1): 43-53. 15.  Darrow, M.C., Dai, W., Mitchell, P.G., Luengo, I., Chiu, W., Duke, E.M.H., (2016). Organelle changes in a Huntington’s Disease model using cryogenic soft X-ray tomography. European Microscopy Congress 2016: Proceedings. 284-285. 16.  Hecksel, C.W., Darrow, M.C., Dai, W., Galaz-Montoya, J.G., Chin, J.A., Mitchell, P.G., Chen S., Jakana, J., Schmid M. F., Chiu, W., (2016). Quantifying variability of manual annotation in cryo-electron tomograms. Microsc Microanal. 22 (3), 487-496. 17.  Tan, Z., Dai, W., van Erp, T.G.M., Overman, J., Demuro, A., Digman, M.A., et al. (2015). Huntington’s disease cerebrospinal fluid seeds aggregation of mutant Huntingtin. Mol. Psychiatry20 (11), 1286-1293. 18.  Dai, W., Fu, C., Khant, H.A., Ludtke, S.J., Schmid, M.F., and Chiu, W. (2014). Zernike phase-contrast electron cryotomography applied to marine cyanobacteria infected with cyanophages. Nat Protoc 9, 2630-2642. 19.  Dai, W., Schmid, M.F., King, J.A., and Chiu, W. (2014). Identifying the assembly pathway of cyanophage inside the marine bacterium using electron cryo-tomography. Microbial Cell 1, 45-47. 20.  Chiu, W., Dai, W., Fu, C., Raytcheva, D., Flanagna, J., Khant, H.A., et al. (2014). Visualizing virus assembly intermediates inside marine cyanobacteria by zernike phase contrast electron cryo-tomography. Microsc. Microanal., 20 (S3), 202-203 21.  Dai, W., Fu, C., Raytcheva, D., Flanagan, J., Khant, H.A., Liu, X., Rochat, R.H., Haase-Pettingell, C., et al. (2013). Visualizing virus assembly intermediates inside marine cyanobacteria. Nature 502, 707-710. 22.  Yu, X., Shah, S., Lee, M., Dai, W., Lo, P., Britt, W., Zhu, H., Liu, F., et al. (2011) Biochemical and structural characterization of the capsid-bound tegument proteins of human cytomegalovirus. J. Struct. Biol. 174 (3), 451-460.  23.  Dai, W., Hodes, A., Hui, W.H., Gingery, M., Miller, J.F., and Zhou, Z.H. (2010). Three-dimensional structure of tropism-switching Bordetella bacteriophage. PNAS 107, 4347-4352. 24.  Dai, W., Jia, Q., Bortz, E., Shah, S., Liu, J., Atanasov, I., Li, X., Taylor, K.A., et al. (2007). Unique structures in a tumor herpesvirus revealed by cryo-electron tomography and microscopy, J. Struct. Biol. 161, 428-438.  25.  Dai, W., Hodes, A., Hui, W., Ge, P., Atanasov, I., Miller, J., Zhou, Z.H., (2006). Structural organization of tropism-switching bordetella bacteriophage revealed by integrative electron cryotomography and cryomicroscopy, Microsc. Microanal., 12 (S02), 418-419. 26.  Dai, W., Liang, Y., and Zhou, Z.H. (2003). Web portal to an image database for high-resolution three-dimensional reconstruction, J. Struct. Biol. 144, 238-245.