The Lab

Welcome to the Dai Lab! 

Located on the second floor of the Proteomics building on Busch campus in Piscataway, our lab is made up of both students and post-doctoral researchers, who tackle difficult questions in many molecular biology fields. Through the use of high-tech bioimaging techniques in conjuction with tried and true methods of molecular biology, we aim to understand the interactions and roles that various proteins may have within the context of cells and their membranes. Using three-dimensional (3D) cryo-electron tomography (cryoET) and correlative light and electron microscopy (CLEM), we are able to capture snapshots of these protein-membrane interactions in a near natural state; the methods used to prepare samples limit possible exposure to damage or disruption of these complexes.  

Some of our current interests are in trying to understand studying mutant Huntingtin transmission, pursuing new anti-fungal targets through yeast, and exploring ultra structural details of thylakoid membranes in marine diatoms.